HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: M3K2 (Q9Y2U5)
Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)
Gene: MAP3K2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.735

The method score is based on:

Property Details
Experiments 33961781, 35271311, 26496610, 32707033, 36736316, 28514442
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 245
Hs

1 619
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024