HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: HECD4 (Q9Y4D8)
Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4)
Gene: HECTD4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	28514442, 15161933
Identification Methods	anti tag coimmunoprecipitation, pull down
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 3996
+	Hs
		101690 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		F8VWT9_HUMAN (1-3996): 0: 7767: 99.03
+	Hs
		101681 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		F8VWT9_HUMAN (1-3996): 0: 7767: 99.03
+	Hs
		125351 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		WWP2_HUMAN (3351-3991): 2.41e-145: 479: 16.52
+	Hs
		125318 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		WWP2_HUMAN (3351-3991): 2.41e-145: 479: 16.52
+	Hs
		125169 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		WWP2_HUMAN (3351-3991): 2.41e-145: 479: 16.52
+	Mm
		808343 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		NEDD4_MOUSE (3553-3991): 6.15e-141: 467: 18.86
+	Hs
		808081 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		NEDD4_HUMAN (3553-3991): 4.33e-135: 463: 18.86
+	Rn
		910358 1433E_RAT (2-241): 9.9e-144: 403: 68.18		NEDD4_RAT (3388-3991): 7.09e-140: 464: 16.04
+	Hs
		927423 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		NED4L_HUMAN (3482-3991): 2.77e-138: 462: 17.77
+	Mm
		93264 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		E9PXB7_MOUSE (3482-3991): 2.05e-140: 464: 17.97
+	Hs
		808077 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		NEDD4_HUMAN (3553-3991): 4.33e-135: 463: 18.86
+	Hs
		909930 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		NED4L_HUMAN (3482-3991): 2.77e-138: 462: 17.77
+	Mm
		910302 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		NED4L_MOUSE (3482-3991): 5.13e-138: 462: 17.97
+	Hs
		647267 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		WWP1_HUMAN (3457-3991): 7.23e-141: 468: 17.98
+	Hs
		647191 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ITCH_HUMAN (3457-3991): 1.65e-140: 466: 18.22
+	Hs
		646713 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		NEDD4_HUMAN (3553-3991): 4.33e-135: 463: 18.86
+	Hs
		647201 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		NED4L_HUMAN (3482-3991): 2.77e-138: 462: 17.77
+	At
		788566 14333_ARATH (3-239): 1.48e-141: 398: 64.73		UPL2_ARATH (3535-3994): 3.29e-128: 458: 20.22
+	Mm
		926792 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		HERC2_MOUSE (3554-3989): 1.73e-110: 400: 27.07
+	Mm
		926831 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q80W01_MOUSE (3698-3996): 8.21e-125: 397: 95.99