Interactor 1: UBE2B (P63146)
Ubiquitin-conjugating enzyme E2 B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme B) (RAD6 homolog B) (HR6B) (hHR6B) (Ubiquitin carrier protein B) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase B)
Gene: UBE2B
Interactor 2: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.991 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25582440, 28514442, 33961781, 35355521, 19549727, 15359278, 21549715, 17720710, 27569044, 27377895, 10908344, 10884424, 31873223, 18363965, 33508099, 35313791, 21422291, 21858012, 20675655, 18245774 and 2 others
more... |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, biochemical, x-ray crystallography, surface plasmon resonance, nuclear magnetic resonance, anti tag coimmunoprecipitation, two hybrid array |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UQ_con~zf-C3HC4_2 |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005657 - replication fork GO:0005737 - cytoplasm GO:0006281 - DNA repair and 4 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
