Interactor 1: HMGB1 (P63158)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: RAGE (Q62151)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: Ager

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 22842346
Identification Methods enzyme linked immunosorbent assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0010508 - positive regulation of autophagy
and 8 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 215
Mm

1 402
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024