HitPredict

Interactor 1: RSMN (P63162)
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)
Gene: SNRPN

Interactor 2: DHX35 (Q9H5Z1)
Probable ATP-dependent RNA helicase DHX35 (EC 3.6.4.13) (DEAH box protein 35)
Gene: DHX35

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 240 Hs			1 703
+	Hs
		539149 RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43		DHX35_HUMAN (1-703): 0: 1005: 100.00
+	Hs
		538958 RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43		DHX8_HUMAN (34-701): 0: 970: 46.65
+	Hs
		195334 RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43		DHX15_HUMAN (41-698): 0: 926: 44.05
+	Sc
		622315 RSMB_YEAST (1-165): 2.64e-36: 128: 28.72		PRP22_YEAST (7-700): 0: 916: 44.91
+	Hs
		124032 SPT5H_HUMAN (100-228): 4.97e-25: 105: 17.69		PRP16_HUMAN (16-700): 0: 929: 41.92
+	Sc
		766924 RSMB_YEAST (1-165): 2.64e-36: 128: 28.72		PRP43_YEAST (15-701): 0: 885: 43.44
+	Hs
		538921 RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43		DHX9_HUMAN (1-701): 0: 789: 27.01
+	Sc
		589430 RSMB_YEAST (1-165): 2.64e-36: 128: 28.72		PRP2_YEAST (14-686): 0: 794: 37.66
+	Hs
		124001 SPT5H_HUMAN (100-228): 4.97e-25: 105: 17.69		DHX40_HUMAN (23-702): 0: 779: 35.87
+	Sp
		1013605 RSMB_SCHPO (6-156): 1.85e-18: 80.8: 44.74		YK99_SCHPO (32-687): 0: 763: 39.39