Interactor 1: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1
Interactor 2: SAE2 (Q9UBT2)
SUMO-activating enzyme subunit 2 (EC 2.3.2.-) (Anthracycline-associated resistance ARX) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2)
Gene: UBA2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 12924945, 32296183, 10217437, 9920803, 14673145, 20164921, 10187858, 31515488, unassigned1304 |
| Identification Methods | two hybrid, pull down, comigration in sds page, cross-linking study, enzymatic study, two hybrid array, validated two hybrid, two hybrid prey pooling approach |
| Interaction Type | direct interaction, other modification, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Rad60-SLD~ThiF |
| Common GO terms | GO:0005654 - nucleoplasm GO:0016925 - protein sumoylation GO:0044388 - small protein activating enzyme binding |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
