HitPredict

Interactor 1: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Interactor 2: ARIP4 (Q9Y4B4)
Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2)
Gene: RAD54L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 101 Hs			1 1467
+	Hs
		902820 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		ARIP4_HUMAN (1-1467): 0: 1193: 100.00
+	Hs
		879164 SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42		ARIP4_HUMAN (1-1467): 0: 1193: 100.00
+	Hs
		802413 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		ATRX_HUMAN (23-1102): 0: 618: 28.83
+	Ce
		879058 SUMO_CAEEL (9-97): 4.4e-34: 114: 58.43		Q18241_CAEEL (97-1005): 0: 601: 32.72
+	Hs
		928205 SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00		CHD8_HUMAN (5-1340): 1.18e-174: 581: 15.27
+	Hs
		928081 SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00		CHD3_HUMAN (108-1366): 5.26e-175: 575: 14.30
+	Dm
		332484 O97102_DROME (11-98): 1.01e-36: 120: 51.14		CHDM_DROME (59-1285): 2.99e-179: 587: 15.26
+	Hs
		902761 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		CHD8_HUMAN (5-1340): 1.18e-174: 581: 15.27
+	Hs
		846913 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		SMCA4_HUMAN (23-1125): 2.79e-179: 580: 17.04
+	Hs
		902587 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		CHD4_HUMAN (68-1302): 2.04e-177: 580: 13.79
+	Hs
		879157 SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42		CHD8_HUMAN (5-1340): 1.18e-174: 581: 15.27
+	Sc
		603350 SMT3_YEAST (3-99): 7.04e-32: 109: 47.42		SNF2_YEAST (100-1194): 0: 593: 17.45
+	Hs
		902554 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		CHD3_HUMAN (108-1366): 5.26e-175: 575: 14.30
+	Hs
		928198 SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00		SMRCD_HUMAN (19-911): 2.76e-174: 550: 19.04
+	Hs
		928239 SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00		RA54B_HUMAN (260-914): 1.05e-175: 550: 26.77
+	Hs
		902754 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		SMRCD_HUMAN (19-911): 2.76e-174: 550: 19.04
+	Hs
		658709 NF2IP_HUMAN (10-90): 2.19e-25: 99.4: 26.83		SMCA1_HUMAN (169-1098): 0: 572: 18.62
+	At
		878949 SUMO1_ARATH (9-95): 3e-35: 117: 47.13		CHR25_ARATH (260-910): 2.23e-171: 539: 25.90
+	Hs
		928070 SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00		ERCC6_HUMAN (300-891): 1.09e-50: 199: 28.36
+	Hs
		902539 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		ERCC6_HUMAN (300-891): 1.09e-50: 199: 28.36