HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.741

Property	Details
Experiments	25416956, 26496610, 32296183, 33961781, 35271311, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0006915 - apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 851
+	Hs
		1144747 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KANK2_HUMAN (1-851): 0: 559: 100.00
+	Hs
		928334 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		Q5W0W2_HUMAN (483-837): 8.61e-82: 269: 45.26
+	Hs
		928414 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		CTTB2_HUMAN (14-727): 8.07e-23: 107: 11.75
+	Hs
		1264904 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		CTTB2_HUMAN (14-727): 8.07e-23: 107: 11.75
+	Hs
		928299 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KANK1_HUMAN (732-850): 2.2e-19: 95.9: 23.81
+	Hs
		1057147 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KANK1_HUMAN (732-850): 2.2e-19: 95.9: 23.81
+	Hs
		928341 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KANK3_HUMAN (90-850): 3.12e-16: 85.5: 14.77