HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: MRCKG (Q6DT37)
Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 1551
+	Hs
		1150626 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MRCKG_HUMAN (1-1551): 0: 1461: 100.00
+	Hs
		928384 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MINK1_HUMAN (47-1344): 0: 620: 15.64
+	Rn
		928573 DYL1_RAT (1-89): 1.96e-46: 145: 100.00		MARK3_RAT (17-767): 1.42e-143: 462: 14.93
+	Hs
		928460 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		SIK2_HUMAN (60-847): 1.11e-139: 456: 16.26
+	Hs
		148656 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		CTRO_HUMAN (11-871): 6.09e-129: 446: 26.03
+	Hs
		568621 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KAPCA_HUMAN (43-371): 1.08e-128: 406: 33.14
+	Hs
		568762 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KAPCA_HUMAN (43-371): 1.08e-128: 406: 33.14