HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: MINK1 (Q8N4C8)
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
Gene: MINK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32707033, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 1332
+	Hs
		324784 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		928339 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MRCKG_HUMAN (6-1299): 0: 652: 16.34
+	Hs
		1150626 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MRCKG_HUMAN (6-1299): 0: 652: 16.34
+	Hs
		131563 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		STK25_HUMAN (20-413): 1.71e-119: 380: 37.37
+	Hs
		928545 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		STK24_HUMAN (20-443): 5.39e-117: 374: 34.98
+	Hs
		928392 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		Q8NBY1_HUMAN (16-404): 1.26e-115: 369: 37.34
+	Hs
		928498 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		STK26_HUMAN (16-413): 5.32e-114: 365: 37.00
+	Hs
		1291313 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		STK26_HUMAN (16-413): 5.32e-114: 365: 37.00