HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: NEK9 (Q8TD19)
Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)
Gene: NEK9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.751

Property	Details
Experiments	26496610, 27173435, 33961781, 35271311, 25852190, 36736316, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 979
+	Hs
		1254363 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		NEK9_HUMAN (1-979): 0: 1056: 100.00
+	Rn
		928573 DYL1_RAT (1-89): 1.96e-46: 145: 100.00		MARK3_RAT (2-481): 1.07e-135: 428: 20.00
+	Hs
		1291277 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		NEK1_HUMAN (52-311): 4.47e-61: 229: 42.31
+	Hs
		928409 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		NEK7_HUMAN (58-304): 2.53e-48: 176: 39.29
+	Hs
		928475 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		NEK6_HUMAN (58-297): 1.69e-46: 171: 39.68