Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: DYL2 (Q96FJ2)
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Gene: DYNLL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 35271311, 27173435, 33961781, 35235311, 34349018, 36652389, 17353931
Identification Methods affinity chromatography technology, cross-linking study, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Dynein_light~Dynein_light
Common GO terms GO:0005634 - nucleus
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005868 - cytoplasmic dynein complex
and 6 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 89
Hs

1 89
+ Dm
+ Hs
+ Ce
+ Hs
+ At
+ Hs
+ Hs
+ At
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024