HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	30217970, 33961781, 35271311
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule GO:1904115 - axon cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 345
+	Mm
		928561 DYL1_MOUSE (1-89): 1.96e-46: 145: 100.00		NDEL1_MOUSE (1-345): 7.05e-67: 215: 95.94
+	Hs
		1291290 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		NDEL1_HUMAN (1-345): 1.8e-67: 217: 100.00
+	Mm
		928560 DYL1_MOUSE (1-89): 1.96e-46: 145: 100.00		NDE1_MOUSE (3-345): 7.34e-47: 164: 54.31
+	Hs
		928493 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		1291310 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		928476 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MYO10_HUMAN (36-324): 1.73e-29: 121: 15.92
+	Hs
		148656 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		1189784 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MYH14_HUMAN (2-216): 1.78e-13: 73.5: 19.54
+	Hs
		928414 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		CTTB2_HUMAN (1-342): 7.57e-11: 65.4: 13.50
+	Hs
		1264904 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		CTTB2_HUMAN (1-342): 7.57e-11: 65.4: 13.50
+	Hs
		928339 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MRCKG_HUMAN (11-286): 7.32e-09: 59.3: 11.42
+	Hs
		1150626 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MRCKG_HUMAN (11-286): 7.32e-09: 59.3: 11.42