HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 335
+	Hs
		1291310 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		NDE1_HUMAN (1-335): 2.68e-70: 224: 100.00
+	Mm
		928561 DYL1_MOUSE (1-89): 1.96e-46: 145: 100.00		NDEL1_MOUSE (3-316): 7.82e-68: 217: 57.73
+	Hs
		928458 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78
+	Mm
		928560 DYL1_MOUSE (1-89): 1.96e-46: 145: 100.00		NDE1_MOUSE (1-310): 6.47e-66: 212: 91.29
+	Hs
		1291290 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78
+	Hs
		1189784 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MYH14_HUMAN (2-211): 4.08e-18: 87.7: 17.62