HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: STK26 (Q9P289)
Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)
Gene: STK26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	35271311, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 416
+	Hs
		1291313 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		STK26_HUMAN (1-416): 1.59e-158: 455: 100.00
+	Hs
		928392 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		Q8NBY1_HUMAN (1-416): 1.17e-148: 428: 94.23
+	Hs
		928545 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		STK24_HUMAN (17-411): 1.47e-137: 402: 70.69
+	Hs
		131563 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		STK25_HUMAN (14-411): 7.15e-134: 392: 68.63
+	Hs
		568621 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KAPCA_HUMAN (22-326): 1.68e-130: 381: 25.56
+	Hs
		610709 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KAPCB_HUMAN (15-324): 8.54e-131: 381: 24.69
+	Hs
		609658 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KAPCG_HUMAN (14-326): 1e-129: 379: 24.92
+	Hs
		568762 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KAPCA_HUMAN (22-326): 1.68e-130: 381: 25.56
+	Hs
		610764 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KAPCB_HUMAN (15-324): 8.54e-131: 381: 24.69
+	Hs
		609686 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KAPCG_HUMAN (14-326): 1e-129: 379: 24.92
+	Hs
		928278 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		PAK1_HUMAN (16-299): 6.42e-121: 363: 44.41
+	Hs
		1026205 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		PAK1_HUMAN (16-299): 6.42e-121: 363: 44.41