HitPredict

Interactor 1: DYL1 (P63168)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN) (mPIN)
Gene: Dynll1

Interactor 2: NDE1 (Q9CZA6)
Nuclear distribution protein nudE homolog 1 (NudE) (mNudE)
Gene: NDE1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	21911489, 11163258
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0005874 - microtubule GO:0019904 - protein domain specific binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 89 Mm			1 344
+	Hs
		928458 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		NDEL1_HUMAN (3-342): 1.13e-78: 246: 54.49
+	Hs
		1291290 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		NDEL1_HUMAN (3-342): 1.13e-78: 246: 54.49
+	Hs
		928493 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		NDE1_HUMAN (1-311): 7.19e-78: 243: 91.00
+	Hs
		1291310 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		NDE1_HUMAN (1-311): 7.19e-78: 243: 91.00
+	Mm
		928561 DYL1_MOUSE (1-89): 1.96e-46: 145: 100.00		NDEL1_MOUSE (3-342): 1.02e-75: 238: 54.78
+	Hs
		928414 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		CTTB2_HUMAN (36-343): 1.06e-58: 206: 15.09
+	Hs
		1264904 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		CTTB2_HUMAN (36-343): 1.06e-58: 206: 15.09
+	Hs
		1189784 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MYH14_HUMAN (2-203): 1.24e-29: 121: 19.31