HitPredict

Interactor 1: DYLT1 (P63172)
Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog)
Gene: DYNLT1

Interactor 2: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26638075, 27173435, 28718761
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005868 - cytoplasmic dynein complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 113 Hs			1 536
+	Hs
		1262253 DYT2B_HUMAN (2-110): 2.72e-36: 122: 29.09		DC2I2_HUMAN (1-536): 4.45e-110: 340: 100.00
+	Hs
		1127237 DYLT4_HUMAN (2-111): 9.76e-27: 100: 19.47		DC2I2_HUMAN (1-536): 4.45e-110: 340: 100.00
+	Hs
		928590 DYLT1_HUMAN (1-113): 1.19e-51: 160: 100.00		DC1I2_HUMAN (42-536): 9.49e-73: 245: 19.69
+	Dm
		1096837 DYLT_DROME (5-113): 9.87e-45: 142: 70.64		DYIN_DROME (67-534): 3.7e-79: 262: 20.91
+	Hs
		148060 DYLT1_HUMAN (1-113): 1.19e-51: 160: 100.00		DC1I1_HUMAN (11-536): 2.11e-70: 239: 18.44
+	Cr
		65480 O04355_CHLRE (7-111): 1.81e-37: 124: 24.53		A8IJZ3_CHLRE (1-530): 5.13e-83: 270: 19.67
+	Hs
		850528 DYLT3_HUMAN (1-113): 1.14e-46: 147: 54.39		DC1I2_HUMAN (42-536): 9.49e-73: 245: 19.69
+	Hs
		148055 DYLT3_HUMAN (1-113): 1.14e-46: 147: 54.39		DC1I1_HUMAN (11-536): 2.11e-70: 239: 18.44
+	Hs
		792965 DYLT1_HUMAN (1-113): 1.19e-51: 160: 100.00		LIS1_HUMAN (262-536): 4.91e-63: 213: 11.63
+	Hs
		792944 DYLT3_HUMAN (1-113): 1.14e-46: 147: 54.39		LIS1_HUMAN (262-536): 4.91e-63: 213: 11.63
+	Hs
		793018 DYT2B_HUMAN (2-110): 2.72e-36: 122: 29.09		LIS1_HUMAN (262-536): 4.91e-63: 213: 11.63
+	Hs
		928646 DYLT1_HUMAN (1-113): 1.19e-51: 160: 100.00		DC2I1_HUMAN (63-496): 4.07e-27: 118: 19.05
+	Hs
		1261757 DYT2B_HUMAN (2-110): 2.72e-36: 122: 29.09		DC2I1_HUMAN (63-496): 4.07e-27: 118: 19.05
+	Hs
		1127235 DYLT4_HUMAN (2-111): 9.76e-27: 100: 19.47		DC2I1_HUMAN (63-496): 4.07e-27: 118: 19.05