Interactor 1: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1

Interactor 2: FBX11 (Q86XK2)
F-box only protein 11 (Protein arginine N-methyltransferase 9) (Vitiligo-associated protein 1) (VIT-1)
Gene: FBXO11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 25416956, 27705803, 33961781, 28614300, 30254149, 29892012, 17098746, 22113614, 23478441, 20596027, 22632967, 31515488
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~Skp1
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 163
Hs

1 927
+ Dm
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024