Interactor 1: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1

Interactor 2: FBH1 (Q8NFZ0)
F-box DNA helicase 1 (hFBH1) (EC 5.6.2.4) (DNA 3'-5' helicase 1) (F-box only protein 18)
Gene: FBH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 27705803, 11956208, 33961781, 30596474, 31130363, 15118074, 23319600
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~Skp1
Common GO terms GO:0005634 - nucleus
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 163
Hs

1 1043
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024