HitPredict

Interactor 1: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1

Interactor 2: FBX32 (Q969P5)
F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)
Gene: FBXO32

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.661

Property	Details
Experiments	26753747, 23414517, 11717410
Identification Methods	affinity chromatography technology, two hybrid, pull down, two hybrid fragment pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination and 1 others more... GO:0019005 - SCF ubiquitin ligase complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 163 Hs			1 355
+	Mm
		1321638 SKP1_MOUSE (1-163): 8.88e-88: 255: 99.39		FBX32_MOUSE (1-355): 0: 549: 96.62
+	Hs
		929003 SKP1_HUMAN (1-163): 1.62e-87: 254: 100.00		FBX25_HUMAN (1-355): 0: 527: 59.89
+	Dm
		285034 O77430_DROME (1-163): 1.01e-79: 235: 76.69		Q9VTM4_DROME (1-353): 1.16e-130: 379: 26.39