HitPredict

Interactor 1: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 27705803, 33961781, 27234298, 30190310, 31257023, 31560077, 24035498
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~Skp1
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 163
Hs

1 701
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Last updated: 15 Jul 2024