HitPredict

Interactor 1: IF5A1 (P63241)
Eukaryotic translation initiation factor 5A-1 (eIF-5A-1) (eIF-5A1) (Eukaryotic initiation factor 5A isoform 1) (eIF-5A) (Rev-binding factor) (eIF-4D)
Gene: EIF5A

Interactor 2: IF5A2 (Q9GZV4)
Eukaryotic translation initiation factor 5A-2 (eIF-5A-2) (eIF-5A2) (Eukaryotic initiation factor 5A isoform 2)
Gene: EIF5A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

The method score is based on:

Property	Details
Experiments	33961781, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	eIF-5a~eIF-5a
Common GO terms	GO:0003723 - RNA binding GO:0003746 - translation elongation factor activity GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol and 4 others more... GO:0006414 - translational elongation GO:0043022 - ribosome binding GO:0045901 - positive regulation of translational elongation GO:0045905 - positive regulation of translational termination
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	154
Hs

1	153

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024