HitPredict

Interactor 1: RACK1 (P63244)
Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Interactor 2: TXNIP (Q9H3M7)
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29378950
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007049 - cell cycle GO:0043065 - positive regulation of apoptotic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 391
+	Hs
		929606 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		ARRD3_HUMAN (2-383): 9.54e-131: 383: 40.35
+	Hs
		1281387 FBXW7_HUMAN (3-128): 4.32e-21: 95.4: 24.63		TXNIP_HUMAN (1-391): 1.4e-149: 430: 100.00
+	Dm
		836162 TAF5_DROME (57-282): 7.29e-17: 83.2: 28.95		Q9I7K8_DROME (10-374): 8.78e-99: 302: 16.83
+	Sc
		742955 GBLP_YEAST (5-138): 5.08e-18: 84.6: 19.68		ROD1_YEAST (45-301): 1.63e-35: 140: 13.61