Interactor 1: KCNJ2 (P63252)
Inward rectifier potassium channel 2 (Cardiac inward rectifier potassium channel) (Inward rectifier K(+) channel Kir2.1) (IRK-1) (hIRK1) (Potassium channel, inwardly rectifying subfamily J member 2)
Gene: KCNJ2

Interactor 2: KCJ15 (Q99712)
ATP-sensitive inward rectifier potassium channel 15 (Inward rectifier K(+) channel Kir1.3) (Inward rectifier K(+) channel Kir4.2) (Potassium channel, inwardly rectifying subfamily J member 15)
Gene: KCNJ15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRK~IRK, IRK~IRK_C, IRK_C~IRK_C
Common GO terms GO:0005242 - inward rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport
GO:0034765 - regulation of monoatomic ion transmembrane transport
GO:1990573 - potassium ion import across plasma membrane
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 427
Hs

1 375
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024