HitPredict

Interactor 1: ACTG (P63260)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: Actg1

Interactor 2: GIT1 (Q68FF6)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1)
Gene: GIT1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19022416
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0044305 - calyx of Held GO:0045202 - synapse
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 375 Mm			1 770
+	Hs
		929860 ACTG_HUMAN (1-375): 0: 604: 100.00		GIT2_HUMAN (1-768): 1.45e-139: 431: 63.71
+	Hs
		60342 ACTBL_HUMAN (2-375): 0: 734: 91.44		POTEF_HUMAN (52-620): 2.03e-40: 162: 12.59
+	Hs
		965115 ACTBL_HUMAN (2-375): 0: 734: 91.44		ANK2_HUMAN (89-573): 7.15e-31: 133: 11.72
+	Hs
		474804 ACTB_HUMAN (1-375): 0: 604: 98.93		POTEI_HUMAN (52-620): 1.73e-40: 162: 12.93
+	Hs
		474872 ACTB_HUMAN (1-375): 0: 604: 98.93		POTEJ_HUMAN (52-620): 2.78e-40: 161: 13.10
+	Hs
		891845 ACTB_HUMAN (1-375): 0: 604: 98.93		POTEE_HUMAN (52-620): 2.12e-39: 159: 12.41
+	Hs
		929902 ACTG_HUMAN (1-375): 0: 604: 100.00		POTEE_HUMAN (52-620): 2.12e-39: 159: 12.41
+	Hs
		474805 ACTC_HUMAN (2-375): 0: 595: 94.39		POTEI_HUMAN (52-620): 1.73e-40: 162: 12.93
+	Hs
		60318 ACTC_HUMAN (2-375): 0: 595: 94.39		POTEF_HUMAN (52-620): 2.03e-40: 162: 12.59
+	Hs
		474874 ACTC_HUMAN (2-375): 0: 595: 94.39		POTEJ_HUMAN (52-620): 2.78e-40: 161: 13.10
+	Rn
		251023 ACTB_RAT (1-375): 0: 604: 98.93		ANK3_RAT (174-715): 9.62e-33: 139: 11.30
+	Hs
		891699 ACTB_HUMAN (1-375): 0: 604: 98.93		ANK2_HUMAN (89-573): 7.15e-31: 133: 11.72
+	Hs
		930079 ACTH_HUMAN (2-375): 0: 592: 94.39		ANK2_HUMAN (89-573): 7.15e-31: 133: 11.72