Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.921

The method score is based on:

Property Details
Experiments 25416956, 16189514, 21516116, 25910212
Identification Methods two hybrid, two hybrid array, split luciferase complementation, two hybrid bait and prey pooling approach, validated two hybrid, two hybrid pooling approach, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Actin
Common GO terms GO:0001525 - angiogenesis
GO:0001738 - morphogenesis of a polarized epithelium
GO:0005200 - structural constituent of cytoskeleton
GO:0005522 - profilin binding
GO:0005524 - ATP binding
and 42 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 375
Hs

1 375
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024