Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 14743216
Identification Methods tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 375
Hs

1 716
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024