HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005884 - actin filament GO:0005886 - plasma membrane and 1 others more... GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 1084
+	Hs
		891813 ACTB_HUMAN (1-375): 0: 604: 98.93		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		724859 ACTBL_HUMAN (2-375): 0: 734: 91.44		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		1122431 ACTBL_HUMAN (2-375): 0: 734: 91.44		SRCAP_HUMAN (828-1033): 1.6e-09: 64.6: 21.40
+	Hs
		929920 ACTG_HUMAN (1-375): 0: 604: 100.00		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Mm
		929785 ACTG_MOUSE (1-375): 0: 604: 100.00		SMCA4_MOUSE (46-592): 1.64e-32: 139: 12.94
+	Hs
		846910 ACTB_HUMAN (1-375): 0: 604: 98.93		SMCA4_HUMAN (46-592): 7.62e-32: 137: 12.59
+	Hs
		846917 ACTG_HUMAN (1-375): 0: 604: 100.00		SMCA4_HUMAN (46-592): 7.62e-32: 137: 12.59
+	Hs
		930015 ACTG_HUMAN (1-375): 0: 604: 100.00		MYO5C_HUMAN (338-916): 1.21e-17: 91.1: 10.24
+	Mm
		892205 ACTB_MOUSE (1-375): 0: 604: 98.93		MYH9_MOUSE (51-655): 2.19e-15: 83.8: 9.15
+	Rn
		892228 ACTB_RAT (1-375): 0: 604: 98.93		MYH9_RAT (284-736): 4.28e-15: 82.7: 10.71
+	Hs
		724738 ACTB_HUMAN (1-375): 0: 604: 98.93		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		724762 ACTG_HUMAN (1-375): 0: 604: 100.00		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Rn
		892236 ACTB_RAT (1-375): 0: 604: 98.93		MYH10_RAT (479-879): 1.3e-12: 74.5: 11.79
+	Hs
		724766 ACTC_HUMAN (2-375): 0: 595: 94.39		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Rn
		92841 ACTB_RAT (1-375): 0: 604: 98.93		CTRO_RAT (533-855): 7.07e-11: 69.1: 11.15
+	Hs
		891853 ACTB_HUMAN (1-375): 0: 604: 98.93		SRCAP_HUMAN (828-1033): 1.6e-09: 64.6: 21.40
+	Hs
		929905 ACTG_HUMAN (1-375): 0: 604: 100.00		SRCAP_HUMAN (828-1033): 1.6e-09: 64.6: 21.40
+	Hs
		148662 ACTC_HUMAN (2-375): 0: 595: 94.39		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		891760 ACTB_HUMAN (1-375): 0: 604: 98.93		DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85
+	Hs
		929862 ACTG_HUMAN (1-375): 0: 604: 100.00		DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85