HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: ENAH (Q8N8S7)
Protein enabled homolog
Gene: ENAH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005522 - profilin binding GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0005925 - focal adhesion and 1 others more... GO:0045202 - synapse
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 591
+	Hs
		1122440 ACTBL_HUMAN (2-375): 0: 734: 91.44		HOME1_HUMAN (1-285): 2.84e-39: 149: 15.64
+	Hs
		891898 ACTB_HUMAN (1-375): 0: 604: 98.93		ENAH_HUMAN (1-591): 2.13e-77: 258: 100.00
+	Hs
		932262 ACTC_HUMAN (2-375): 0: 595: 94.39		ENAH_HUMAN (1-591): 2.13e-77: 258: 100.00
+	Hs
		357 ACTB_HUMAN (1-375): 0: 604: 98.93		A0A075B6E5_HUMAN (1-162): 2.4e-58: 196: 74.69
+	Hs
		358 ACTG_HUMAN (1-375): 0: 604: 100.00		A0A075B6E5_HUMAN (1-162): 2.4e-58: 196: 74.69
+	Hs
		891932 ACTB_HUMAN (1-375): 0: 604: 98.93		CTTB2_HUMAN (87-571): 1.34e-43: 169: 13.08
+	Hs
		891877 ACTB_HUMAN (1-375): 0: 604: 98.93		HOME1_HUMAN (1-285): 2.84e-39: 149: 15.64
+	Hs
		930047 ACTG_HUMAN (1-375): 0: 604: 100.00		TNIK_HUMAN (129-587): 5.09e-30: 128: 17.86
+	Hs
		930044 ACTG_HUMAN (1-375): 0: 604: 100.00		EVL_HUMAN (1-374): 7.41e-27: 115: 32.71
+	Hs
		892049 ACTB_HUMAN (1-375): 0: 604: 98.93		MYO10_HUMAN (182-480): 4.53e-25: 112: 14.15
+	Hs
		930011 ACTG_HUMAN (1-375): 0: 604: 100.00		MYO10_HUMAN (182-480): 4.53e-25: 112: 14.15
+	Hs
		840448 ACTB_HUMAN (1-375): 0: 604: 98.93		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		840454 ACTG_HUMAN (1-375): 0: 604: 100.00		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		840455 ACTC_HUMAN (2-375): 0: 595: 94.39		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		892089 ACTB_HUMAN (1-375): 0: 604: 98.93		SWP70_HUMAN (84-269): 5.97e-14: 76.9: 25.00