HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: UBS3B (Q8TF42)
Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)
Gene: UBASH3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24189400
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031625 - ubiquitin protein ligase binding GO:0070527 - platelet aggregation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 649
+	Hs
		891919 ACTB_HUMAN (1-375): 0: 604: 98.93		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		883321 ACTB_HUMAN (1-375): 0: 604: 98.93		UBS3A_HUMAN (12-643): 0: 947: 43.37
+	Hs
		891671 ACTB_HUMAN (1-375): 0: 604: 98.93		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924453 ACTG_HUMAN (1-375): 0: 604: 100.00		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924456 ACTC_HUMAN (2-375): 0: 595: 94.39		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924454 ACTH_HUMAN (2-375): 0: 592: 94.39		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		932316 ACTC_HUMAN (2-375): 0: 595: 94.39		SH3K1_HUMAN (221-375): 5.02e-29: 124: 25.00
+	Hs
		282322 ACTB_HUMAN (1-375): 0: 604: 98.93		NEBL_HUMAN (249-318): 1.57e-19: 95.6: 32.39
+	Hs
		235496 ACTS_HUMAN (2-375): 0: 594: 93.85		VINEX_HUMAN (229-317): 1e-22: 104: 26.97
+	Hs
		892005 ACTB_HUMAN (1-375): 0: 604: 98.93		SRBS1_HUMAN (258-317): 1.89e-18: 92.2: 40.00
+	Hs
		932362 ACTC_HUMAN (2-375): 0: 595: 94.39		SRBS1_HUMAN (258-317): 1.89e-18: 92.2: 40.00
+	Mm
		915552 ACTA_MOUSE (2-375): 0: 594: 94.39		LASP1_MOUSE (203-315): 1.68e-18: 87.5: 21.88
+	Dm
		501505 ACT1_DROME (2-375): 0: 600: 98.13		LASP1_DROME (258-317): 3.37e-15: 81: 38.33
+	Dm
		361146 ACT2_DROME (2-375): 0: 598: 97.59		LASP1_DROME (258-317): 3.37e-15: 81: 38.33
+	Dm
		501447 ACT5_DROME (2-375): 0: 598: 95.46		LASP1_DROME (258-317): 3.37e-15: 81: 38.33
+	Dm
		862562 ACT3_DROME (2-375): 0: 596: 94.92		LASP1_DROME (258-317): 3.37e-15: 81: 38.33
+	Dm
		950121 ACT6_DROME (2-375): 0: 596: 95.46		LASP1_DROME (258-317): 3.37e-15: 81: 38.33
+	Hs
		891770 ACTB_HUMAN (1-375): 0: 604: 98.93		LASP1_HUMAN (254-315): 1.29e-12: 70.2: 30.65
+	Hs
		596202 ACTB_HUMAN (1-375): 0: 604: 98.93		NEBU_HUMAN (256-315): 6.87e-11: 67.9: 33.33
+	Hs
		596210 ACTH_HUMAN (2-375): 0: 592: 94.39		NEBU_HUMAN (256-315): 6.87e-11: 67.9: 33.33