Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: DCTN4 (Q9UJW0)
Dynactin subunit 4 (Dyn4) (Dynactin subunit p62)
Gene: DCTN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28718761, 35271311
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Dynactin_p62
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005925 - focal adhesion
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 375
Hs

1 460
+ Hs
+ Hs

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Last updated: 15 Jul 2024