HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005925 - focal adhesion GO:0045202 - synapse GO:0051893 - regulation of focal adhesion assembly
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 474
+	Hs
		892108 ACTB_HUMAN (1-375): 0: 604: 98.93		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		932449 ACTC_HUMAN (2-375): 0: 595: 94.39		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		932355 ACTC_HUMAN (2-375): 0: 595: 94.39		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		903280 ACTBL_HUMAN (2-375): 0: 734: 91.44		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		903316 POTEE_HUMAN (1-375): 0: 729: 91.47		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		932318 ACTC_HUMAN (2-375): 0: 595: 94.39		SNR40_HUMAN (160-435): 1.36e-38: 145: 11.87
+	Hs
		932185 ACTC_HUMAN (2-375): 0: 595: 94.39		RBBP7_HUMAN (14-341): 1.13e-35: 139: 18.94
+	Hs
		891943 ACTB_HUMAN (1-375): 0: 604: 98.93		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		929956 ACTG_HUMAN (1-375): 0: 604: 100.00		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		884627 ACTB_HUMAN (1-375): 0: 604: 98.93		CORO7_HUMAN (2-203): 2.45e-23: 105: 12.22
+	Sc
		887686 ACT_YEAST (1-375): 0: 592: 89.07		CORO_YEAST (2-228): 2.02e-24: 108: 12.16
+	Hs
		891660 ACTB_HUMAN (1-375): 0: 604: 98.93		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		903110 ACTG_HUMAN (1-375): 0: 604: 100.00		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39