HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 721
+	Hs
		892144 ACTB_HUMAN (1-375): 0: 604: 98.93		LRRF2_HUMAN (1-721): 7.69e-104: 335: 100.00
+	Hs
		932480 ACTC_HUMAN (2-375): 0: 595: 94.39		LRRF2_HUMAN (1-721): 7.69e-104: 335: 100.00
+	Hs
		891807 ACTB_HUMAN (1-375): 0: 604: 98.93		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		929885 ACTG_HUMAN (1-375): 0: 604: 100.00		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		724859 ACTBL_HUMAN (2-375): 0: 734: 91.44		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		932190 ACTC_HUMAN (2-375): 0: 595: 94.39		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Mm
		892205 ACTB_MOUSE (1-375): 0: 604: 98.93		MYH9_MOUSE (218-628): 1.68e-13: 76.8: 9.44
+	Hs
		929935 ACTG_HUMAN (1-375): 0: 604: 100.00		DLG5_HUMAN (219-569): 1.09e-12: 74.1: 10.72
+	Hs
		891935 ACTB_HUMAN (1-375): 0: 604: 98.93		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		929952 ACTG_HUMAN (1-375): 0: 604: 100.00		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Rn
		892236 ACTB_RAT (1-375): 0: 604: 98.93		MYH10_RAT (466-719): 7.5e-11: 67.9: 16.93
+	Rn
		892228 ACTB_RAT (1-375): 0: 604: 98.93		MYH9_RAT (331-715): 1.22e-10: 67.2: 13.51
+	Hs
		932297 ACTC_HUMAN (2-375): 0: 595: 94.39		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		724738 ACTB_HUMAN (1-375): 0: 604: 98.93		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		724762 ACTG_HUMAN (1-375): 0: 604: 100.00		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		933030 ACTS_HUMAN (2-375): 0: 594: 93.85		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		725136 ACTC_HUMAN (2-375): 0: 595: 94.39		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Hs
		725135 ACTH_HUMAN (2-375): 0: 592: 94.39		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Hs
		724766 ACTC_HUMAN (2-375): 0: 595: 94.39		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		724767 ACTS_HUMAN (2-375): 0: 594: 93.85		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12