HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: WASF2 (Q9Y6W5)
Actin-binding protein WASF2 (Protein WAVE-2) (Verprolin homology domain-containing protein 2) (Wiskott-Aldrich syndrome protein family member 2) (WASP family protein member 2)
Gene: WASF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0001525 - angiogenesis GO:0005829 - cytosol GO:0005911 - cell-cell junction GO:0045202 - synapse GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 498
+	Hs
		892150 ACTB_HUMAN (1-375): 0: 604: 98.93		WASF2_HUMAN (1-498): 3.76e-64: 218: 100.00
+	Hs
		932482 ACTC_HUMAN (2-375): 0: 595: 94.39		WASF2_HUMAN (1-498): 3.76e-64: 218: 100.00
+	Hs
		930055 ACTG_HUMAN (1-375): 0: 604: 100.00		WASF3_HUMAN (1-498): 4.08e-58: 202: 46.92
+	Hs
		929950 ACTG_HUMAN (1-375): 0: 604: 100.00		WASF1_HUMAN (1-496): 3.22e-43: 162: 43.19
+	Rn
		892225 ACTB_RAT (1-375): 0: 604: 98.93		WASF1_RAT (1-496): 1.76e-41: 157: 43.19
+	Hs
		203220 ACTC_HUMAN (2-375): 0: 595: 94.39		SYNJ1_HUMAN (36-496): 2.09e-41: 161: 13.30
+	Hs
		891942 ACTB_HUMAN (1-375): 0: 604: 98.93		CBP_HUMAN (38-468): 2.79e-27: 118: 12.79
+	Hs
		915464 ACTA_HUMAN (2-375): 0: 594: 94.39		CBP_HUMAN (38-468): 2.79e-27: 118: 12.79