HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 31575873, 8610150, 20936779, 21139563, 8668125, 8940097, 21988832, 20061386
Identification Methods enzymatic study, two hybrid, pull down, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~UQ_con
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000795 - synaptonemal complex
GO:0001221 - transcription coregulator binding
GO:0003723 - RNA binding
GO:0005524 - ATP binding
and 26 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 158
Hs

1 158
+ Hs
+ Zm
+ Hs
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ Sc
+ Hs
+ Sc
+ Zm
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024