HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	32296183, 24260396
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 568
+	Hs
		849318 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00
+	Hs
		849315 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRAF2_HUMAN (11-565): 1.77e-110: 340: 30.21
+	Hs
		1377466 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRAF6_HUMAN (22-562): 7.2e-84: 272: 21.28
+	Hs
		1204911 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI50_HUMAN (43-481): 2.78e-57: 201: 12.74
+	Hs
		584907 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RO52_HUMAN (47-480): 6.99e-58: 202: 11.06
+	Hs
		537142 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI27_HUMAN (40-481): 5.22e-53: 190: 11.37
+	Hs
		536760 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRI27_HUMAN (40-481): 5.22e-53: 190: 11.37
+	Hs
		1163056 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRAF7_HUMAN (43-440): 1.17e-48: 181: 15.17
+	Hs
		1313765 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI62_HUMAN (47-494): 3.27e-47: 173: 9.22
+	Hs
		1285831 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI43_HUMAN (39-480): 2.28e-45: 167: 12.66
+	Hs
		1052807 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI25_HUMAN (46-374): 4.38e-42: 162: 16.08
+	Hs
		849330 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRI25_HUMAN (46-374): 4.38e-42: 162: 16.08
+	Hs
		1357712 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI35_HUMAN (32-441): 2.72e-41: 157: 11.48
+	Hs
		1336390 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI39_HUMAN (44-418): 1.23e-38: 150: 14.70
+	Mm
		895982 UB2D1_MOUSE (4-157): 7.96e-75: 221: 33.12		RNF41_MOUSE (38-213): 2.04e-30: 123: 19.89
+	Hs
		1290204 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN125_HUMAN (21-181): 4.4e-29: 117: 21.77
+	Hs
		1377468 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN114_HUMAN (46-200): 7.9e-28: 113: 15.92
+	Hs
		1283434 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN166_HUMAN (44-210): 9.16e-26: 107: 23.26
+	Hs
		301690 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRI37_HUMAN (39-322): 1.6e-14: 78.9: 12.98
+	Hs
		1252560 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		LNX1_HUMAN (28-174): 2.64e-11: 68.4: 22.45