HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21113135
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 604
+	Hs
		849321 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		919721 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		849322 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC2_HUMAN (2-604): 0: 643: 72.31
+	Hs
		919722 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		BIRC2_HUMAN (2-604): 0: 643: 72.31
+	Hs
		957802 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21
+	Hs
		849308 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21
+	Hs
		919707 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21
+	Hs
		849387 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RFFL_HUMAN (254-604): 6.11e-54: 189: 15.88
+	Hs
		919804 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		RFFL_HUMAN (254-604): 6.11e-54: 189: 15.88
+	Hs
		849456 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC6_HUMAN (7-136): 3.42e-35: 144: 20.29
+	Hs
		849400 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC7_HUMAN (13-165): 1.87e-34: 134: 21.80
+	Hs
		1298970 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		BIRC8_HUMAN (166-287): 8.71e-28: 113: 30.83
+	Hs
		849413 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC8_HUMAN (166-287): 8.71e-28: 113: 30.83
+	Dm
		639392 UBCD1_DROME (4-157): 4.5e-74: 220: 35.71		DIAP1_DROME (20-173): 1.43e-24: 108: 24.36
+	Hs
		1264347 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		MYLIP_HUMAN (479-603): 3.16e-23: 104: 25.60
+	Hs
		849386 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		MYLIP_HUMAN (479-603): 3.16e-23: 104: 25.60
+	Hs
		919803 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		MYLIP_HUMAN (479-603): 3.16e-23: 104: 25.60
+	Hs
		919809 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		RNF34_HUMAN (547-604): 6.54e-19: 90.8: 36.21
+	Hs
		849396 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		MIB2_HUMAN (544-603): 2.9e-10: 65.3: 35.00
+	Hs
		919813 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		MIB2_HUMAN (544-603): 2.9e-10: 65.3: 35.00