HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25416956, 32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 568
+	Hs
		1120773 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00
+	Dm
		1181452 Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44		KLHDB_DROME (3-566): 3.83e-171: 500: 42.23
+	Hs
		849329 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		KEAP1_HUMAN (8-564): 2.73e-161: 475: 35.88
+	Hs
		307160 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		KLHL2_HUMAN (13-567): 3.8e-158: 466: 41.36
+	Hs
		307190 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		KLHL2_HUMAN (13-567): 3.8e-158: 466: 41.36
+	Hs
		307165 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		KLHL2_HUMAN (13-567): 3.8e-158: 466: 41.36
+	Hs
		828997 UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56		KEAP1_HUMAN (8-564): 2.73e-161: 475: 35.88
+	Hs
		849471 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06
+	Hs
		849470 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		KLHL9_HUMAN (380-568): 3.91e-43: 164: 27.55
+	Hs
		895941 UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07		KLHL3_HUMAN (422-568): 1.81e-34: 139: 36.05