HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: TLK2 (Q86UE8)
Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)
Gene: TLK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007059 - chromosome segregation GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 772
+	Hs
		1183279 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		TLK2_HUMAN (1-754): 0: 585: 100.00
+	Zm
		13349 A0A1D6FSE0_MAIZE (4-157): 1.37e-74: 221: 35.71		A0A1Q0ZG94_MAIZE (31-771): 4.2e-142: 451: 15.52
+	Zm
		35309 A0A1D6LKH6_MAIZE (1-154): 6.82e-67: 202: 38.31		A0A1Q0ZG94_MAIZE (31-771): 4.2e-142: 451: 15.52
+	Hs
		829021 UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56		PKN3_HUMAN (3-767): 7.75e-126: 399: 14.76
+	At
		1105323 SCE1_ARATH (2-155): 5.4e-72: 215: 66.23		KIN10_ARATH (456-754): 1.1e-124: 384: 28.09
+	Zm
		8408 A0A1D6ENM7_MAIZE (2-157): 5.13e-75: 223: 35.90		Q6RXY1_MAIZE (447-754): 2.87e-107: 339: 27.60
+	Hs
		1039098 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		KCC2D_HUMAN (457-743): 5.04e-106: 335: 28.57
+	Hs
		930200 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		KCC2D_HUMAN (457-743): 5.04e-106: 335: 28.57