HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: BIRC7 (Q96CA5)
Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]
Gene: BIRC7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21113135
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 298
+	Hs
		849400 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC7_HUMAN (1-298): 4.39e-104: 307: 100.00
+	Hs
		849456 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC6_HUMAN (54-252): 6.52e-36: 138: 21.10
+	Hs
		1264347 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		MYLIP_HUMAN (152-297): 3.79e-26: 108: 22.45
+	Hs
		849386 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		MYLIP_HUMAN (152-297): 3.79e-26: 108: 22.45
+	Hs
		919803 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		MYLIP_HUMAN (152-297): 3.79e-26: 108: 22.45
+	Hs
		849396 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		MIB2_HUMAN (236-297): 7.71e-23: 100: 38.71
+	Hs
		282379 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		NEUL1_HUMAN (167-298): 1.14e-22: 99.6: 22.46
+	Dm
		639392 UBCD1_DROME (4-157): 4.5e-74: 220: 35.71		DIAP1_DROME (77-253): 8.76e-22: 96.6: 20.23
+	Hs
		1206094 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		MIB1_HUMAN (206-296): 7.37e-20: 91.6: 25.28
+	Hs
		849321 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC3_HUMAN (240-298): 5.43e-20: 92: 71.67
+	Hs
		849363 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		MIB1_HUMAN (206-296): 7.37e-20: 91.6: 25.28
+	Hs
		919721 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		BIRC3_HUMAN (240-298): 5.43e-20: 92: 71.67
+	Hs
		919776 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		MIB1_HUMAN (206-296): 7.37e-20: 91.6: 25.28
+	Hs
		849322 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC2_HUMAN (84-281): 4.95e-19: 88.9: 23.23
+	Hs
		919722 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		BIRC2_HUMAN (84-281): 4.95e-19: 88.9: 23.23
+	Hs
		1298970 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		BIRC8_HUMAN (1-96): 5.33e-17: 80.4: 18.18
+	Hs
		849413 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		BIRC8_HUMAN (1-96): 5.33e-17: 80.4: 18.18
+	Hs
		957802 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		XIAP_HUMAN (1-96): 3.35e-13: 71.5: 19.19
+	Hs
		849308 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		XIAP_HUMAN (1-96): 3.35e-13: 71.5: 19.19
+	Hs
		919707 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		XIAP_HUMAN (1-96): 3.35e-13: 71.5: 19.19