HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: GMCL1 (Q96IK5)
Germ cell-less protein-like 1 (Spermatogenesis-associated protein 29)
Gene: GMCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	27107012, 32296183
Identification Methods	two hybrid, barcode fusion genetics two hybrid, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 515
+	Hs
		1183303 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		1183286 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		GMCL2_HUMAN (1-513): 0: 538: 90.84
+	Hs
		307160 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		KLHL2_HUMAN (16-347): 1.66e-73: 245: 15.02
+	Hs
		849329 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		KEAP1_HUMAN (31-360): 4.2e-73: 245: 15.00
+	Hs
		895941 UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07		KLHL3_HUMAN (62-346): 2.37e-75: 250: 17.48
+	Hs
		1120773 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		KLH12_HUMAN (81-393): 9.98e-75: 248: 16.24
+	Hs
		307190 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		KLHL2_HUMAN (16-347): 1.66e-73: 245: 15.02
+	Hs
		930247 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		KLH12_HUMAN (81-393): 9.98e-75: 248: 16.24
+	Dm
		1181452 Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44		KLHDB_DROME (22-347): 1.04e-77: 257: 18.02
+	Hs
		307165 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		KLHL2_HUMAN (16-347): 1.66e-73: 245: 15.02
+	Hs
		828997 UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56		KEAP1_HUMAN (31-360): 4.2e-73: 245: 15.00