Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: KMT5A (Q9NQR1)
N-lysine methyltransferase KMT5A (EC 2.1.1.-) (H4-K20-HMTase KMT5A) (Histone-lysine N-methyltransferase KMT5A) (EC 2.1.1.361) (Lysine N-methyltransferase 5A) (Lysine-specific methylase 5A) (PR/SET domain-containing protein 07) (PR-Set7) (PR/SET07) (SET domain-containing protein 8)
Gene: KMT5A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 21829513
Identification Methods two hybrid, affinity chromatography technology, pull down, enzymatic study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0045892 - negative regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 158
Hs

1 393
+ Zm
+ Hs
+ Dm
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024