HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UBA~UQ_con, UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 624
+	Hs
		1183317 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1183320 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		930454 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		829086 UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Dm
		639410 UBCD1_DROME (4-157): 4.5e-74: 220: 35.71		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Hs
		895774 UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		895773 UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		70479 UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77		B2RDW1_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Sc
		819482 UBC7_YEAST (1-149): 9.95e-31: 110: 38.13		DSK2_YEAST (32-239): 1.13e-31: 128: 31.19