HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	17391059, 23772552
Identification Methods	affinity chromatography technology, two hybrid, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 1281
+	Hs
		1033668 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		930194 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Mm
		930484 UBC9_MOUSE (1-158): 1.43e-70: 211: 100.00		IKZF1_MOUSE (781-1272): 1.75e-99: 329: 17.80
+	Mm
		140044 UBC9_MOUSE (1-158): 1.43e-70: 211: 100.00		IKZF3_MOUSE (783-1268): 4.76e-82: 280: 17.04
+	Hs
		930448 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		930394 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		IKZF5_HUMAN (909-1270): 9.35e-58: 207: 17.46
+	Mm
		570288 UBC9_MOUSE (1-158): 1.43e-70: 211: 100.00		GATA1_MOUSE (804-1033): 5.18e-40: 155: 20.21
+	Hs
		930306 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		ZN420_HUMAN (833-1092): 1.57e-19: 96.9: 9.41