HitPredict

Interactor 1: UBC9 (P63280)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (mUBC9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I)
Gene: Ube2i

Interactor 2: NR2C1 (Q505F1)
Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2) (mTR2)
Gene: NR2C1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	17187077
Identification Methods	anti bait coimmunoprecipitation, two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 158 Mm			1 590
+	Hs
		823785 UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07		NR2C2_HUMAN (15-590): 1.42e-151: 450: 58.45
+	Hs
		823730 UB2E1_HUMAN (3-156): 7.23e-67: 203: 33.12		NR2C2_HUMAN (15-590): 1.42e-151: 450: 58.45
+	Hs
		130320 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		NR5A2_HUMAN (19-579): 2.76e-111: 345: 21.95
+	Hs
		930249 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		Q58EY0_HUMAN (94-577): 3.88e-92: 292: 20.29
+	Hs
		930190 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		STF1_HUMAN (94-579): 3.33e-87: 280: 21.01
+	Hs
		265861 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		NR1I2_HUMAN (78-574): 5.77e-79: 257: 17.46
+	Hs
		587151 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		RXRA_HUMAN (23-240): 5.87e-52: 186: 27.12
+	Hs
		782515 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		HNF4A_HUMAN (72-209): 4.78e-44: 165: 39.13