HitPredict

Interactor 1: PP2BA (P63328)
Protein phosphatase 3 catalytic subunit alpha (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin A alpha) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha) (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform)
Gene: Ppp3ca

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 27507650, 28671696, 19455133
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~PDZ
Common GO terms GO:0005737 - cytoplasm
GO:0043197 - dendritic spine
GO:0044877 - protein-containing complex binding
GO:0045202 - synapse
GO:0098978 - glutamatergic synapse
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 521
Mm

1 724
+ Mm
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+ Hs
+ Mm
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Last updated: 15 Jul 2024