HitPredict

Interactor 1: PP2AA (P63330)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16)
Gene: Ppp2ca

Interactor 2: KSR1 (Q61097)
Kinase suppressor of Ras 1 (mKSR1) (EC 2.7.11.1) (Protein Hb)
Gene: KSR1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12932319
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0046872 - metal ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 309 Mm			1 873
+	Hs
		915235 PP2AB_HUMAN (1-309): 0: 529: 97.41		KSR1_HUMAN (1-873): 0: 695: 85.17
+	Gg
		819348 PP2AA_CHICK (1-309): 0: 530: 98.06		BRAF_CHICK (98-854): 1.25e-151: 466: 22.49
+	Hs
		542859 PP2AA_HUMAN (1-309): 0: 531: 99.68		BRAF_HUMAN (123-854): 1.9e-150: 463: 22.84
+	Hs
		542850 PP2AB_HUMAN (1-309): 0: 529: 97.41		BRAF_HUMAN (123-854): 1.9e-150: 463: 22.84
+	Mm
		655939 PP2AB_MOUSE (1-309): 0: 529: 97.41		BRAF_MOUSE (123-854): 3.96e-146: 451: 22.46
+	Hs
		374028 PP2AA_HUMAN (1-309): 0: 531: 99.68		RAF1_HUMAN (240-858): 1.26e-144: 444: 24.45
+	Hs
		374005 PP2AB_HUMAN (1-309): 0: 529: 97.41		RAF1_HUMAN (240-858): 1.26e-144: 444: 24.45
+	Hs
		542848 PP1A_HUMAN (4-296): 0: 503: 46.36		BRAF_HUMAN (123-854): 1.9e-150: 463: 22.84
+	Mm
		655937 PP1A_MOUSE (4-296): 0: 503: 46.69		BRAF_MOUSE (123-854): 3.96e-146: 451: 22.46
+	Hs
		373800 PP1G_HUMAN (4-306): 0: 505: 45.83		RAF1_HUMAN (240-858): 1.26e-144: 444: 24.45
+	At
		984290 PP2A1_ARATH (8-309): 0: 505: 80.13		CTR1_ARATH (500-832): 7.29e-99: 328: 28.15