HitPredict

Interactor 1: APT (P63544)
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7)
Gene: APT

Interactor 2: APT (P63544)
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7)
Gene: APT

Species: Streptococcus pneumoniae TIGR4

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19098921
Identification Methods	miniaturized immunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pribosyltran~Pribosyltran
Common GO terms	GO:0002055 - adenine binding GO:0003999 - adenine phosphoribosyltransferase activity GO:0005737 - cytoplasm GO:0006166 - purine ribonucleoside salvage GO:0006168 - adenine salvage and 2 others more... GO:0016208 - AMP binding GO:0044209 - AMP salvage
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 170 Sp			1 170
+	At
		678696 APT3_ARATH (3-170): 1.02e-81: 240: 41.67		APT1_ARATH (3-169): 2.03e-78: 234: 44.31
+	At
		1337904 APT3_ARATH (3-170): 1.02e-81: 240: 41.67		APT5_ARATH (3-169): 5.62e-77: 229: 40.72
+	At
		678692 APT1_ARATH (3-169): 2.03e-78: 234: 44.31		APT1_ARATH (3-169): 2.03e-78: 234: 44.31
+	At
		1115025 APT3_ARATH (3-170): 1.02e-81: 240: 41.67		APT2_ARATH (3-169): 5.98e-76: 226: 42.52
+	At
		678694 APT1_ARATH (3-169): 2.03e-78: 234: 44.31		APT5_ARATH (3-169): 5.62e-77: 229: 40.72
+	At
		1115024 APT5_ARATH (3-169): 5.62e-77: 229: 40.72		APT2_ARATH (3-169): 5.98e-76: 226: 42.52
+	Cj
		1351494 APT_CAMJE (3-169): 6.59e-71: 213: 40.59		APT_CAMJE (3-169): 6.59e-71: 213: 40.59
+	Ec
		935879 APT_ECOLI (3-170): 3.36e-70: 212: 48.82		APT_ECOLI (3-170): 3.36e-70: 212: 48.82
+	Sc
		828080 APT1_YEAST (3-167): 2.41e-60: 187: 39.65		APT1_YEAST (3-167): 2.41e-60: 187: 39.65
+	Sc
		739415 APT1_YEAST (3-167): 2.41e-60: 187: 39.65		APT2_YEAST (3-167): 3.62e-56: 176: 33.14
+	Sp
		474083 PYRE_STRPN (37-170): 9.9e-30: 109: 19.85		PYRE_STRPN (37-170): 9.9e-30: 109: 19.85