HitPredict

Interactor 1: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Interactor 2: IGBP1 (P78318)
Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16)
Gene: IGBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.98	1.00	0.990

Property	Details
Experiments	24484909, 23892082, 26496610, 23591866, 32296183, 16085932, 33961781, 9647778, 20092282, 21454489, 21988832, 27880917, 28330616, 18782753, 10441131, 35271311, 19156129, 24145130, 22167190, unassigned1304
Identification Methods	affinity chromatography technology, pull down, x-ray crystallography, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, two hybrid array, tandem affinity purification, validated two hybrid, two hybrid prey pooling approach and 1 others more... anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Metallophos~TAP42
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Hs			1 339
+	Hs
		915159 PP2AB_HUMAN (1-309): 0: 528: 97.41		IGBP1_HUMAN (1-339): 3.66e-137: 394: 100.00
+	Mm
		915326 PP2AB_MOUSE (1-309): 0: 528: 97.41		IGBP1_MOUSE (2-339): 5.16e-130: 376: 80.47
+	Mm
		930632 PP2AA_MOUSE (1-309): 0: 528: 99.68		IGBP1_MOUSE (2-339): 5.16e-130: 376: 80.47
+	Hs
		890950 PP4C_HUMAN (4-309): 0: 508: 64.82		IGBP1_HUMAN (1-339): 3.66e-137: 394: 100.00
+	Dm
		619912 PP2A_DROME (1-309): 0: 524: 93.85		Q9VJZ5_DROME (11-338): 6.94e-99: 298: 29.57
+	Ce
		108339 PP2A_CAEEL (3-309): 0: 519: 89.25		PP4RS_CAEEL (12-339): 6.68e-99: 297: 30.03
+	Ce
		1341622 PP4C1_CAEEL (3-309): 0: 504: 62.14		PP4RS_CAEEL (12-339): 6.68e-99: 297: 30.03
+	Dm
		284474 PP4C_DROME (9-309): 9.82e-178: 494: 63.58		Q9VJZ5_DROME (11-338): 6.94e-99: 298: 29.57
+	At
		990795 PP2A3_ARATH (7-309): 0: 511: 80.86		TAP46_ARATH (12-336): 8.62e-86: 266: 21.41
+	At
		990786 PP2A2_ARATH (9-309): 0: 509: 80.07		TAP46_ARATH (12-336): 8.62e-86: 266: 21.41
+	At
		138692 PP2A5_ARATH (7-309): 0: 508: 80.20		TAP46_ARATH (12-336): 8.62e-86: 266: 21.41
+	At
		820006 PP2A4_ARATH (7-309): 0: 508: 80.86		TAP46_ARATH (12-336): 8.62e-86: 266: 21.41
+	At
		990790 PP2A1_ARATH (9-309): 0: 505: 80.40		TAP46_ARATH (12-336): 8.62e-86: 266: 21.41
+	At
		819524 PPX1_ARATH (7-309): 1.73e-178: 496: 64.59		TAP46_ARATH (12-336): 8.62e-86: 266: 21.41
+	Sc
		618797 PP2A1_YEAST (10-309): 0: 517: 76.00		TAP42_YEAST (26-339): 3.88e-75: 237: 23.82
+	Sc
		618860 PP2A2_YEAST (10-309): 0: 514: 76.67		TAP42_YEAST (26-339): 3.88e-75: 237: 23.82
+	Sp
		619322 PP2A2_SCHPO (5-309): 0: 504: 79.02		YCJ5_SCHPO (27-339): 1.73e-66: 213: 24.57
+	Sp
		619311 PP2A1_SCHPO (7-309): 1.75e-179: 499: 79.54		YCJ5_SCHPO (27-339): 1.73e-66: 213: 24.57
+	At
		1227771 FYPP3_ARATH (9-309): 1.67e-135: 387: 57.62		TAP46_ARATH (12-336): 8.62e-86: 266: 21.41
+	Sc
		594364 PP11_YEAST (11-309): 1.47e-137: 393: 57.71		TAP42_YEAST (26-339): 3.88e-75: 237: 23.82