HitPredict

Interactor 1: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Interactor 2: 2A5E (Q16537)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon)
Gene: PPP2R5E

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.971

Property	Details
Experiments	8703017, 26496610, 27880917, 28330616, 18782753, 35271311, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	B56~Metallophos
Common GO terms	GO:0000159 - protein phosphatase type 2A complex GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Hs			1 467
+	Hs
		915202 PP2AB_HUMAN (1-309): 0: 528: 97.41		2A5E_HUMAN (1-467): 0: 773: 100.00
+	Hs
		92474 PP2AA_HUMAN (1-309): 0: 529: 100.00		E9PFR3_HUMAN (4-454): 0: 708: 67.91
+	Hs
		930847 PP2AA_HUMAN (1-309): 0: 529: 100.00		2A5D_HUMAN (4-454): 0: 708: 67.91
+	Dm
		619908 PP2A_DROME (1-309): 0: 524: 93.85		Q9VEC6_DROME (48-457): 0: 712: 68.77
+	Hs
		915191 PP2AB_HUMAN (1-309): 0: 528: 97.41		2A5D_HUMAN (4-454): 0: 708: 67.91
+	Mm
		915336 PP2AB_MOUSE (1-309): 0: 528: 97.41		Q91V89_MOUSE (4-454): 0: 707: 68.13
+	Mm
		930650 PP2AA_MOUSE (1-309): 0: 528: 99.68		Q91V89_MOUSE (4-454): 0: 707: 68.13
+	Hs
		930853 PP2AA_HUMAN (1-309): 0: 529: 100.00		2A5A_HUMAN (12-434): 0: 705: 80.43
+	Hs
		915194 PP2AB_HUMAN (1-309): 0: 528: 97.41		2A5A_HUMAN (12-434): 0: 705: 80.43
+	Dm
		619900 PP2A_DROME (1-309): 0: 524: 93.85		Q9VB23_DROME (11-463): 0: 704: 75.77
+	Hs
		930854 PP2AA_HUMAN (1-309): 0: 529: 100.00		2A5B_HUMAN (2-463): 0: 696: 71.92
+	Hs
		915195 PP2AB_HUMAN (1-309): 0: 528: 97.41		2A5B_HUMAN (2-463): 0: 696: 71.92
+	Hs
		890964 PP4C_HUMAN (4-309): 0: 508: 64.82		2A5D_HUMAN (4-454): 0: 708: 67.91
+	Hs
		930833 PP2AA_HUMAN (1-309): 0: 529: 100.00		2A5G_HUMAN (38-457): 0: 685: 70.76
+	Hs
		915180 PP2AB_HUMAN (1-309): 0: 528: 97.41		2A5G_HUMAN (38-457): 0: 685: 70.76
+	Hs
		890958 PP4C_HUMAN (4-309): 0: 508: 64.82		2A5G_HUMAN (38-457): 0: 685: 70.76
+	Hs
		737787 PP1G_HUMAN (7-306): 0: 505: 45.96		2A5G_HUMAN (38-457): 0: 685: 70.76
+	Sc
		618770 PP2A1_YEAST (10-309): 0: 517: 76.00		2A5D_YEAST (9-462): 0: 621: 50.73
+	Sc
		618834 PP2A2_YEAST (10-309): 0: 514: 76.67		2A5D_YEAST (9-462): 0: 621: 50.73
+	Sp
		619312 PP2A2_SCHPO (5-309): 0: 504: 79.02		2AD2_SCHPO (28-457): 0: 602: 51.27